8 comments

  • lemonberry 1 hour ago
    As the sole caregiver for a father with dementia I can tell you it's a nightmare.

    If you have children please, please plan for late life care. And if you're going to be caring for either of your parents start planning and build a support network. By the time I knew I needed help I was drowning. Learn how to ask for help. I thought I was a relatively progressive 50 year old man, but it turns out help is a 4-letter word.

    • saltcured 2 minutes ago
      My sympathies.

      As hard as it is, supporting family members also need to learn to prioritize taking care of themselves and avoiding a spiral towards burnout. With dementia, there is often a time when the patient needs a more controlled environment with 24x7 supervision. Dementia sleep schedules and behaviors fall apart and are not really compatible with a family caregiver's own health needs.

      Depending on the dementia case, risky behaviors may emerge at night, and having observant caregivers awake 24x7 may be very important. The financial picture for this is quite difficult in the US. Normally this requires a care facility at some point, as it is impossibly expensive to bring sufficient dementia care via visiting professionals.

      To safely handle dementia with "sundowning" and wandering behaviors, you usually need a facility that has about a dozen residents or more. Then, budgets allow for multiple onsite staff and overnight wakeful staff. This can bring more distinct staff roles too, e.g. cooking and housekeeping versus care.

      Even this may be overwhelmingly costly, to the point where the dementia ends up depleting the estate and then shifting to some kind of government support. For family or trustees managing this process, it is full of difficult decisions regarding budget and care tradeoffs. For example, do you splurge on "nicer" facilities or other caregiver factors early on, or try to reserve more funds for the inevitable crises? Dementia can be a drawn-out process, where care needs expand to a crescendo before collapsing back to hospice care, which may be more like other terminal illnesses.

    • d4mi3n 4 minutes ago
      You have my condolences. I helped my wife care for her late father with Lewy body dementia. I think many people recognize they may need to care for the people that raised them at some point, but the realities of the costs--both financially and emotionally--are rarely discussed. @lemonberry feel free to reach out if you need a friendly ear, my email is in my profile.

      On a personal note to anyone in this situation: Do not go it alone. Being a caregiver is hard, but being a caregiver for someone with serious memory issues is brutal and requires 24/7 monitoring. Your loved one will not always cooperate. They may change into someone who does not resemble the person you knew. Many states require such persons to be homed somewhere with a 24/7 nursing staff. Plan accordingly.

  • hodgehog11 1 hour ago
    Given that recent Nature paper which claims that a lithium depletion could be responsible for Alzheimer's disease, is there any mechanism that could link increased air pollution to a reduction in lithium levels?
    • cluckindan 59 minutes ago
      Exposure to another similar metal could in theory displace lithium in biological processes.
  • Drunk_Engineer 39 minutes ago
    Literally car-brained.
    • CalRobert 30 minutes ago
      Nice to know I've got bits of tire in my brain.
  • bethekidyouwant 7 minutes ago
    For a brief fleeting moment, man was not plagued by indoor air pollution nor outdoor air pollution
  • pacifika 1 hour ago
    Proves ULEZ is the right call.
    • echelon_musk 43 minutes ago
      I wish all diesels could be included in the ULEZ ban. Or at minimum all non commercial diesel engines.

      As a motorbike rider I can taste the diesel fumes as soon as I'm behind one in a way that's unlike any petrol car.

      There's large particulates being thrown out by even the most luxurious diesel cars that you simply couldn't tell if you're behind in a car.

    • 0x1ceb00da 56 minutes ago
      Current AQI in london ULEZ is 48 according to google maps which is not that good. Does that mean AQI is not a very good measure of air quality?
      • CJefferson 5 minutes ago
        I don't know the current average, but it used to often be much higher than that. Maybe the average has improved?
      • cinntaile 30 minutes ago
        It doesn't really make sense what you're saying. First you say it's not good but then you question the index. You're clearly using the AQI to base your opinion on? To answer the ULEZ question you should compare to not having ULEZ there, which is what the GP was talking about.
        • 0x1ceb00da 1 minute ago
          Right so london aqi used to be much worse but ULEZ helped.
  • knowitnone2 51 minutes ago
    well, long-term exposure to outdoor air pollution already shortens their lifespan so they won't even live long enough to reach the average age for dementia
    • sillyfluke 30 minutes ago
      Well, the Yuramal in Colombia are the people that hold the record for the most Alzeihmer cases because many possess the gene for early onset and exhibit the diseases at 40 year of age. So for them the age is quite young. This goes to show that currently the record is held by genetic factors and not environmental factors.

      But they also show that it instead of eliminating the root cause of the disease, the solution might be eliminating its symptoms instead. Cause one woman who had the gene defied all odds and exhibited the symptom of the disease in her 70s. The reasoning is that another gene she had, the Christchurch gene, protected her brain from the disease. So if someone can use that info to prevent symptoms of the disease eliminating the root cause would become secondary.

      • jt2190 22 minutes ago
        > ... defied all odds and exhibited the symptom of the disease in her 70s.

        I assume you mean: "exhibited no symptoms of the disease until her 70s".

        Other than luck, did they have any idea why she was able to resist the disease for so long?

  • aaron695 8 minutes ago
    [dead]